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MRZ 2-514
CAS No. 202808-11-5
MRZ 2-514( 8-bromo-4,5-dihydroxypyridazino[4,5-b]quinolin-1-one )
Catalog No. M26308 CAS No. 202808-11-5
MRZ 2-514 is a strychnine-insensitive modulatory site of the NMDA receptor (glycineB)antagonist with Ki of 33 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 664 | Get Quote |
|
| 10MG | 896 | Get Quote |
|
| 25MG | 1467 | Get Quote |
|
| 50MG | 1971 | Get Quote |
|
| 100MG | 2682 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameMRZ 2-514
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NoteResearch use only, not for human use.
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Brief DescriptionMRZ 2-514 is a strychnine-insensitive modulatory site of the NMDA receptor (glycineB)antagonist with Ki of 33 μM.
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DescriptionMRZ 2-514 is a strychnine-insensitive modulatory site of the NMDA receptor (glycineB)antagonist with Ki of 33 μM.(In Vitro):MRZ 2-514 is against peak AMPA-induced currents with IC50 of 72.7 μM.(In Vivo):In mice, MRZ 2-514 has anticonvulsive action in the MES model, and the effect is prolonged by probenecid.
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In VitroMRZ 2-514 has IC50 values against peak AMPA-induced currents of 72.7 μM.
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In VivoMRZ 2/514 has anticonvulsive action in the MES model in mice, and the effect is prolonged by probenecid.
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Synonyms8-bromo-4,5-dihydroxypyridazino[4,5-b]quinolin-1-one
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PathwayMembrane Transporter/Ion Channel
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TargetNMDAR
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number202808-11-5
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Formula Weight308.091
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Molecular FormulaC11H6BrN3O3
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Purity>98% (HPLC)
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Solubility——
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SMILES[O-][n+]1c2ccc(Br)cc2cc2c1c(=O)[nH][nH]c2=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Raymond KN, Dertz EA, Kim SS. Enterobactin: an archetype for microbial iron transport. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3584-8.
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